Description

Celtarys Research (www.celtarys.com), a newly created startup based in Santiago de Compostela (Spain), which develops and commercializes fluorescence-

based innovative chemical tools to improve drug discovery, is looking for a PhD with expertise in Medicinal Chemistry.

She/He will be responsible for the conceptualization, design and execution of internal development projects, funded projects and custom development of

fluorescent probes through the application of Celtarys Technology.

Requirements

• A PhD in Medicinal Chemistry with > 4 years’ experience as post doc.

Extensive and accreditated experience in:

• Organic synthesis: full autonomy in design and realization of multipsteo synthesis (also more than 6-7 steps) for the obtention of complex molecular structure with specific restrictions in terms of stability (such as fluorophores, biomolecules derivatives, etc.);
• Strong and wide knowledge of biomolecules and small molecules purification and characterization approaches;
• Independent design of new molecules able to interact with specific targets of interest;
• Deep understanding of the biological data related to the compounds developed to incorporate them into new designs and/or potential refinement of molecular probes leading to successful experimental outcomes;
• Understanding of molecule/target interaction principles and modes;
• Knowledge of medicinal chemistry basis and approaches to modify molecules structures to improve their bioactivity;
• Strong independence, problem solving, troubleshooting skills and proven ability to lead research projects;
• Responsible and goal-oriented professional, able to integrate into a multidiciscplinary team and work in a competitive environment, dealing with multiple projects and client deadlines.
• Fluent in English
• Experience in the field of fluorescent probes development is a plus.